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Genomics week in brief: Week ending 17th April

Get all the latest genomics news and research all in one place, here, in this week’s genomics week in brief!

Top stories from the past week

  • Researchers have developed a technique that enables them to examine histone modifications in single cells at scale. (Bartosovic et al, 2021)
  • According to new research, individuals with more harmful bacteria in their gums are more likely to have evidence for amyloid beta – a key biomarker for Alzheimer’s disease. (Kamer et al, 2021)
  • Researchers from Hubrecht Institute have developed the first patient-derived organoid model for cervical cancer. (Lõhmussaar et al, 2021)
  • A new test is able to measure the quantity and quality of inactive HIV viruses in the genes of HIV patients, enabling researchers to get a better idea of what drugs may work best. (Levy et al, 2021)
  • Researchers have used genetic engineering tools to modify probiotic yeast to produce beta-carotene in the guts of laboratory mice. (Durmusoglu et al, 2021)
  • A new study has found that a key Ebola virus protein – VP40 – is able to exploit human RNA to change shape, representing a promising therapeutic target. (Landeras-Bueno et al, 2021)
  • New data has provided the first clinical evidence that drug-resistant malaria mutations are gaining in Africa. (Uwimana et al, 2021)
  • Combining two immunotherapy drugs with radiation and surgery is found to increase the survival and immune response in mouse models with mesothelioma. (Murakami et al, 2021)
  • Researchers have used cryo-EM to visualise the process of DNA repair, offering new insights into how proteins identify and resolve double-strand breaks. (Chen et al, 2021)
  • Scientists have shown the fundamental role of epigenetic regulator, HP1a, in the reorganisation of the 3D chromatin structure after fertilisation in Drosophila. (Zenk et al, 2021)


  • Join us on Thursday 22nd April at 3pm BST/4pm CEST/10am EDT for the next webinar in our ‘Cancer Genomics ONLINE’ webinar series. In this webinar, we will explore cancer biomarker discovery and validation as well as the development of precision oncology drugs.
  • Check out the latest webinar in our ‘COVID & Genomics ONLINE’ webinar series. The next webinar will focus on the global research that is detecting and monitoring emerging variants. The webinar is taking place on Wednesday 21st April at 3pm BST/4pm CEST/10am EDT.


  • Download our latest report: ‘Liquid Biopsy: Current Status and Future Directions’. This report will provide you with an overview of liquid biopsy technologies, exclusive interviews with key leaders in the field and insights into the current technical and social barriers impacting clinical uptake.
  • Make sure you check out the latest ‘Sequencing Buyer’s Guide’. This guide will help you understand the sequencing landscape as well as make better purchasing decisions.

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Genomics / Week in brief