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Genomics week in brief: Week ending 23rd January

More genomics news and content – all in one place!

Top stories from the past week

  • Using cryo-EM, researchers have captured the structures of RNA polymerase when in complex with DNA, revealing how its activity changes in response to poor growth conditions. (Murakami et al, 2021)
  • Researchers have defined a cancer invasion machinery, which is orchestrated by the frequently mutated cancer gene Ras. (Klefström et al, 2021)
  • A new study has uncovered the mechanism behind the most severe cases of a common blood disorder – G6PD deficiency. (Wakatsuki et al, 2021)
  • A designer DNA therapeutic has been shown to wipe out cancer stem cells, treating multiple myeloma in mice. (Crews et al, 2021)
  • Scientists have made a pivotal discovery on the mechanism of Epstein-Barr virus latent infection, identifying a previously unknown enzymatic function of EBNA1 viral protein. (Lieberman et al, 2021)
  • Researchers have solved an 100-year-old mystery about cancer by identifying a link between Warburg metabolism and the activity of PI3 kinase. (Xu et al, 2021)
  • A new study of type 2 diabetes in Japanese populations, has uncovered a previously uncharacterised genetic variant that puts male carriers at greater risk for the disease. (Zempo et al, 2021)

In other news

  • The ESHG has warned against coercive collection of DNA, deeming it unethical and damaging to the future of medical research. (Forzano et al, 2021)


  • Join us this week for our annual Festival of Genomics & Biodata. The Festival is the UK’s largest Genomics event. This year we’re expecting over 5,000 attendees from across the globe. It is taking place between 26-29th January – so register now.
  • Join us for our brand-new three-part webinar series – ‘Multi-Omics ONLINE’ . We will be bringing together global experts who are harnessing diverse datasets to advance our understanding of human health and disease. Register now.

More on these topics

Cancer / Genomics / Week in brief