What’s been going on in the life sciences world this week? Check out Week in Brief for an overview of the biggest news from the last seven days.
Research has revealed 20 new mutations in a gene linked to Marfan syndrome, a connective tissue disorder that affects around 1 in 5,000 people in the UK. These new findings could assist in diagnosis.
A new study has described how a harmful bacterial species – Cronobacter sakazakii – survives in dried, powdered foods, particularly baby formula. This new understanding could help to form guidelines and processes to prevent contamination.
New research has shown that inserting a new protein coding gene into the mouse genome could lead to an effect similar to that of a weight loss drug. This one-time approach could have potential for the treatment of obesity and related conditions such as heart disease and diabetes.
Scientists from have developed an at-home diagnostic test that combines plasmonics and AI to assess ‘coffee-ring’ patterns of biomarkers for a range of diseases. The test displayed highly accurate results and could pave the way for more accessible diagnostics.
Scientists have developed a method to trace the evolution of cancer cells using a single tissue sample. By providing a better understanding of how tumours develop, this technique could assist with early detection.
A new study has revealed that genetic risk factors influence the spread of Alzheimer’s-related tau protein in distinct ways, either alongside or independent of the brain’s wiring. Using a novel mathematical model, researchers were able to isolate areas where genetics, rather than neural connections, drive tau accumulation.
A twin study has shown that infants’ sleep and crying patterns are largely genetic. The analysis of 1,000 twin pairs from Sweden showed that the amount of time babies spend crying during the day and their ability to settle are impacted by both their genes and the environment.
Researchers have analysed data from over 13,000 individuals who have used antidepressants, characterising the genetic underpinnings of several common side effects. Understanding people’s risk profiles could help to better personalise treatment plans.
New research has shown that chromosomal abnormalities, specifically tumour aneuploidy, are an effective biomarker for immunotherapy resistance. The work suggests that personalised combination therapies could be used to overcome this challenge.
Finally, an analysis of ancient pathogen genomes and human remains has shown that certain zoonotic diseases were only present in individuals who lived after the emergence of livestock farming. These include both the plague and leprosy.
Check out last week’s Week in Brief here.
