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Key transcription factor for stem cell differentiation linked to cancer

Stem cells are unspecialised cells, defined by their capacity for self-renewal and ability to differentiate into a variety of somatic […]

CRISPR competitor? Deep-learning model for zinc finger design aids transcription factor reprogramming

A new study, published in Nature, outlines an AI-based approach that could help overcome some of the challenges with zinc […]

Genomics study uncovers the transcription factors able to restore hearing in zebrafish

Written by Lauren Robertson, Science Writer. Researchers at the National Human Genome Research Institute (NHGRI) have discovered a unique network […]

Loss of transcription factor alters chromatin accessibility

Researchers have discovered that chromatin accessibility is heavily influenced by a key transcription factor that is linked to cancer. The […]

Japanese Study Identifies 35 Genetic Risk Factors for Atrial Fibrillation

In a new study published in Nature, researchers have identified 35 genetic susceptibility loci for atrial fibrillation (AF) in a […]

How-to: Infer Gene Regulatory Networks from Omics Data

This feature was put together using content from Chapter 5 of the Multi-omics Playbook, released in February 2024. For an […]

How-to: Profile the epigenome

The epigenome regulates the expression of genes without altering their underlying DNA sequence. Comprising a dynamic landscape of chemical modifications […]

Methods to study cell-cell communication from single-cell sequencing data

This feature on cell-cell communication is adapted from part of Chapter 4 of the 2023 Spatial and Single-cell Playbook. Organisms […]

LRRK2 inhibitors offer new hope for Parkinson’s disease

Cellular lysosomal degradative activity is key for healthy cell maintenance. As such, it is unsurprising that changes in the level […]

Genomics week in brief: Week ending 27th May

Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space! Top […]