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Untangling TKI resistance in lung cancer

Written by Charlotte Harrison, Science Writer Non-small cell lung cancer (NSCLC) is often associated with activating mutations in receptor tyrosine […]

Environmental and ecological factors play a significant role in antibiotic resistance

In a recent study, published in the journal eLIFE, researchers have screened over 160,000 bacterial genomes to identify the presence […]

Targeting Pyroptosis – A Promising Strategy for Overcoming Chemotherapy Resistance?

A new study published in Science suggests that targeting pyroptosis, a type of programmed cell death, may be a promising […]

New form of antimicrobial resistance discovered in Group A Streptococcus

Researchers have identified a new form of antimicrobial resistance (AMR) in Group A Streptococcus (GAS). GAS organisms can cause various […]

Predicting chemotherapy resistance in breast and ovarian cancer with BRCA epigenetics

New research discovers genomic and epigenomic BRCA alterations that can predict chemotherapy resistance in breast and ovarian cancers.   A new […]

Overcoming enzalutamide drug resistance in prostate cancer

Scientists have discovered a molecular pathway that may answer why some prostate cancers can resist an approved cancer drug. The […]

Finding biomarkers and mechanisms for chemotherapy resistance in breast cancer

Written by Victoria Lee, Science Writer at Front Line Genomics In the fight against breast cancer, it’s useful to be […]

Researchers Discover Mechanisms of Drug Resistance in Metastatic Colorectal Cancer

Written by Bethany Hoernfeldt, Science Writer  Scientists have revealed a novel mechanism in chemoresistance that may inspire unique approaches to […]

Genomic signatures of pre-resistance in Tuberculosis

Researchers have conducted the largest population-level genomic analysis of M. tuberculosis to date, with a view to pre-empt the emergence of resistance. […]

Genetic signature of treatment resistance in breast cancer identified

Researchers have discovered a genetic signature that can identify drivers of poor outcomes in advanced oestrogen-receptor positive (ER+) breast cancer. […]