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Non-Genetic Mechanisms of Therapeutic Resistance in Cancer

Therapeutic resistance has repeatedly proved itself to be an unconquerable barrier for curative cancer treatment. However, recent investigations have challenged […]

Evolutionary arms race: artificial selection for host resistance to tumour growth

Researchers have used artificial selection to observe the evolutionary arms race between tumour cells and the host immune response. Evolutionary […]

Heterochromatin-dependent processes contribute to fungal resistance

Researchers from the University of Edinburgh have identified how fungal resistance to drugs develops. Originally, researchers thought that only mutations […]

Genome Editing: How to Predict and Detect Collateral Damage

A recent paper, published in Cell, discusses how to anticipate the molecular events that may arise from genome editing and […]

Genomic Epidemiology: The Modern-day Hunt for Malicious Microbes

In this new age of genomic epidemiology, so-called “Microbe Hunters” are combining whole genome sequencing technology with epidemiological data. This […]

HIV: origins, treatment and the continued stigma

The first person to be cured of HIV, Timothy Ray Brown, died last week from a recurrence of leukaemia. His […]

Genomics: Not all doom and gloom

In the past Genomics has faced a lot of controversy, particularly in relation to eugenics. Even today, applications of genomics, […]

Genomic landscape of how cancer cells evade the immune system

Researchers from Donnelly Centre for Cellular and Biomolecular Research at the University of Toronto, have mapped the genes that allow […]

The emergence of liquid biopsy

The applications of liquid biopsy are becoming increasingly apparent – but where did it all begin? Here we explore the […]

Alexander Fleming’s original Penicillium sequenced

Researchers from Imperial College London, CABI and the University of Oxford, have sequenced the genome of Fleming’s original Penicillium strain […]