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World of Genomics: Japan

Original article by Ellie Fung, August 2021. Updated by Kira Newbon in July 2023. In the latest World of Genomics […]

Brain tumour noncoding mutations are new targets for personalised medicine

Traditional cancer driver gene discovery has generally focussed on coding mutations, which can affect protein function and structure. Mutations in […]

UK’s Higher Skin Cancer Rates Defy UV Index

A recent collaboration between the Wellcome Sanger Institute and the Skin Research Institute of Singapore (SRIS) has been published in […]

Genetic Clues for PTSD and Major Depression Discovered

A recent study, published in The American Journal of Psychiatry, has shed light on the mechanisms behind the brain’s response to stress in those with post-traumatic stress disorder (PTSD) and major depressive disorder (MDD). The implications of this study are far-reaching, from improving our understanding of the cellular and molecular basis of PTSD and MDD to potentially revolutionizing the diagnosis and treatment of these challenging neuropsychiatric disorders. The findings open up exciting avenues for further research, personalized medicine, and the development of targeted therapeutic interventions.

LRRK2 inhibitors offer new hope for Parkinson’s disease

Cellular lysosomal degradative activity is key for healthy cell maintenance. As such, it is unsurprising that changes in the level […]

World of Genomics: Romania

Romania has a diverse and idyllic landscape, offering impressive geology, stunning wildlife and a rich cultural history. Much of the […]

Rebalancing immune hyperactivity in Down’s syndrome

Written by Charlotte Harrison, Science Writer  People with Down’s syndrome have chronic hyperactivation of interferon signalling, meaning they are at […]

World of Genomics: Mexico

‘World of Genomics: Mexico’ – Article originally published by Shannon Gunn, November 2021. Updated by Lyndsey Fletcher, July 2023. For […]

Colorectal cancer’s metastatic signature

‘Colorectal cancer’s metastatic signature’ – Written by Charlotte Harrison, Science Writer. Epigenetic changes, such as DNA methylation, are linked to […]

Brain mechanisms of microRNA-132 decoded

‘Brain mechanisms of microRNA-132 decoded’ – Written by Charlotte Harrison, Science Writer. The microRNA miR-132 likely plays a role in […]