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Reversing diabetes with a selective microRNA inhibitor

Researchers have designed a structure-specific microRNA inhibitor that selectively represses a microRNA family member, which may in turn reverse the […]

Cell migration regulators may contribute to cancer metastasis

Researchers have shown that tumour protein D52 (TPD52)-like proteins are important for cell migration and cancer cell invasion, revealing a […]

RNA modifications can protect against non-alcoholic fatty liver disease

Researchers have revealed that post-transcriptional RNA modifications protect against the development of non-alcoholic fatty liver disease. This mechanism may also […]

WHO lays out a framework to regulate human genome editing

A committee established by the World Health Organisation (WHO) has recently published guidelines for the appropriate application of human genome […]

Non-syndromic cleft lip aetiology is illuminated by integrative approaches

In a recent study, researchers integrated existing genomic, epigenomic and transcriptomic data to generate novel insights into the aetiology of […]

A novel pathway in the pathology of Rett syndrome

Researchers have revealed how dysregulation of the MECP2/miR-199a axis may contribute to the molecular pathology of Rett syndrome. Rett syndrome […]

Whole-exome sequencing and the potential for obesity treatment

Researchers have demonstrated the potential of large-scale whole-exome sequencing in facilitating therapeutic target discovery to combat obesity. The recent upsurge […]

Twin studies have disentangled the common genes in post-traumatic stress disorder (PTSD) and migraine

A recent study of monozygotic twins revealed certain genes and pathways that overlap between post-traumatic stress disorder (PTSD) and migraine, […]

The functional importance of unusual DNA structures called G4s has been revealed

For the first time, researchers have found that G-quadruplex structures (G4s) in DNA could be added to the list of […]

HLA-DR4: The human antigen with subtypes that are strongly linked to type 1 diabetes

Researchers have identified three amino acid residues that are responsible for the variable association of HLA-DR4 subtypes with type 1 […]