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How to: perform polygenic risk score analysis

A recent article published in Nature Protocols highlights key issues related to polygenic risk score analyses and provides a starting […]

Polygenic background modifies penetrance of monogenic variants

Researchers have found that polygenic background can modify penetrance of disease in tier 1 genomic conditions. Monogenic variants Monogenic variants […]

Combined risk score predicts type 1 diabetes in children

An article published in Nature Medicine has demonstrated that a combined risk score improves type 1 diabetes (T1D) prediction in […]

Genetic risk for Alzheimer’s progression differs with sex

It is well documented that the genetic risk for Alzheimer’s has a sex bias. Sex bias in Alzheimer’s Carrying a […]

Opinion: Do not rely on your genes to fit into your jeans, genetics-based nutrition is risky business!

Recent times has seen an influx in companies offering direct to consumer genetic tests that offer a wide range of […]

The Genetics Of Alzheimer’s: Uncovering new Mechanisms and Drug Targets

An understanding of the environmental and genetic risk of Alzheimer’s Disease is vital for the production of more effective therapies. […]

Genome UK: The future of healthcare

Genome UK The UK has launched its new National Genomic Healthcare Strategy, with the goal of cementing its status as […]

African genomics needed for genetic medicine

As part of the 20th anniversary of Nature Reviews Genetics, Professor Ambroise Wonkam from the University of Cape Town has […]

Genetic variants linked to male breast cancer found

A recent study published in the Journal of the National Cancer Institute has discovered three genetic variants linked to an […]