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Researchers have revealed novel ultra-rare risk genes for autism

Researchers have identified ultra-rare, likely gene-disruptive variants unique to autism families, revealing 28 novel candidate risk genes. The genetics of […]

Precision medicine in early life may improve adult health outcomes

Researchers have shown that optimising early life nutrition can reduce the risk of adult cardiometabolic disease in genetically predisposed infants, […]

What are ChIP-seq and bisulfite sequencing?

ChIP-seq protocol Chromatin immunoprecipitation sequencing, also known as ChIP-seq, is a method used to analyze protein interactions with DNA. Chromatin […]

How to do RNA sequencing

RNA sequencing is an NGS technique that enables investigation of the transcriptome – the total cellular content of RNAs, including […]

Top single cell isolation techniques

Typically, conventional cell-based research focusses on the average response from a population of cells, without taking into account individual cell […]

What is multiplex PCR?

The polymerase chain reaction (PCR) is a well-established amplification technique that is widely used to rapidly make millions of copies […]

Long-read sequencing vs short-read sequencing

Different sequencing platforms use a variety of read lengths. Both short-read sequencing and long-read sequencing have their own benefits and […]

What are the different types of nucleic acid extraction?

Nucleic acid extraction is the first step in the NGS sample prep protocol. Nucleic acids are large biomolecules that are […]

The progress of NGS platforms

It has been over 30 years since the first generation of DNA sequencing technology was developed in 1977. Since then, […]

A brief history of Next Generation Sequencing (NGS)

Since the discovery of the basic double-helix structure of DNA In the 1950’s, scientists have devoted a huge amount of […]