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Genetic variants impact immune cell function

Researchers have harnessed the power of genome-wide sequencing and functional profiling of immune cells to understand how genetic variants can […]

Eliminating malaria via a simple genetic modification

Researchers have tested genetically modifying mosquitos to express antimalarial genes and pass them on to offspring as a new strategy […]

Chromothripsis: A driver of gene amplification in cancer

Researchers have used whole-genome sequencing (WGS) to show that chromothripsis is a major driver of circular extrachromosomal DNA amplification. Gene […]

Interview with Prof. Diana Baralle, Professor of Genomic Medicine, Honorary Consultant Clinical Genetics, University of Southampton

FLG: Can you introduce yourself and your work? I’m Diana Baralle, a clinical academic specialist in Clinical Genetics with an […]

Genomics week in brief: Week ending 14th January

Check out the latest Genomics Week in Brief covering – full of intriguing news and research from the genomics space! […]

A, C, T to Glossary

Numbers The 1000 Genomes Project: The 1,000 Genome Project (1KGP) launched in January 2008 with the aim of generating the […]

Transcriptome and circular DNA sequencing in single cancer cells

A new single-cell sequencing method has been published in Nature Genetics. Single-cell extrachromosomal circular DNA and transcriptome sequencing (scEC&T-seq) can […]

Genomics week in brief: Week ending 18th March

Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space! Top […]

An overview of cancer biology

Cancer is a disease of the genome. Environmental factors can certainly influence the growth and spread of cancer, but the […]

A guide to cancer genomics

According to the British Journal of Cancer, one in two of us will develop cancer in our lifetime. Despite this […]