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The activity of G-quadruplexes unravelled

Not a lot is known about G-quadruplexes – four-stranded DNA complexes. However, scientists have now developed a new technique to […]

Base editing extends lifespan of mice with progeria

Researchers have successfully used a base editing technique to extend the lifespan of mice with the genetic variant associated with […]

Genomics week in brief: Week ending 9th January

Another week, another genomics week in brief – filled with the latest news and research from the genomics space. Top […]

Chromothripsis: A driver of gene amplification in cancer

Researchers have used whole-genome sequencing (WGS) to show that chromothripsis is a major driver of circular extrachromosomal DNA amplification. Gene […]

Genomics week in brief: Week ending 2nd January

Happy New Year from everyone here at Front Line Genomics! We are kicking the year off with your weekly update […]

Nanopore sequencing combined with liquid biopsy analysis

A recent study, published in Clinical Chemistry, has presented a rapid nanopore genotyping strategy to enable amplification-free identification and classification […]

12 Days of Genomics Christmas

Here at Front Line Genomics, we thought we would spread some Christmas cheer with the 12 days of Christmas but […]

Telomere shortening protects against cancer

New results from Titia de Lange’s lab (at the Rockefeller University) have provided the first piece of evidence that telomere […]

Mythbusters: what mRNA vaccines actually are

“The vaccine will alter my DNA!” “The vaccine will kill millions like others have done!” “Bill Gates is planting a […]

Mitochondrial stress: a phenotype of spaceflight

Spaceflight is known to impact human physiology, but the distinct molecular aetiologies are unknown. In a recent study, published in […]