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Multi-omics: Exploring Inside Cells

Introduction Multi-omics is an emerging field. ‘Omics’ refers to the comprehensive collection of a set of biological molecules. Essentially, the […]

Uncovering processes that drive germline mutations

A new study, published in Science, has used computational analysis to reveal the mechanisms behind germline mutations. Their findings have […]

A, C, T to Glossary

Numbers The 1000 Genomes Project: The 1,000 Genome Project (1KGP) launched in January 2008 with the aim of generating the […]

What are ChIP-seq and bisulfite sequencing?

ChIP-seq protocol Chromatin immunoprecipitation sequencing, also known as ChIP-seq, is a method used to analyze protein interactions with DNA. Chromatin […]

Sample Preparation for NGS – A Comprehensive Guide

Introduction Sample preparation is the process of getting DNA ready for Next Generation Sequencing (NGS). This requires a few steps… […]

Twin studies have disentangled the common genes in post-traumatic stress disorder (PTSD) and migraine

A recent study of monozygotic twins revealed certain genes and pathways that overlap between post-traumatic stress disorder (PTSD) and migraine, […]

Ageing and loss of resilience

Researchers have presented results from a recent study exploring associations between ageing and the loss of the ability to recover […]

Information theory helps identify genes involved in leukaemia

Using a well-known field of mathematics – information theory – researchers have uncovered possible genes involved in the development of […]

Epigenetic clock is accelerated in major depressive disorder

Researchers have found that an epigenetic clock and predictor of mortality – GrimAge – is accelerated in individuals with major […]

3D Genetics, EpiSwitch™️ and Clinical Translation: Development of Liquid Biopsy for Diffuse large B-cell lymphoma prognosis and benchmarking it against digital PCR gold standards

Chromatin exists as a non-linear, “three-dimensional” structure in the nuclear space, and refers to the complex of DNA and proteins […]