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DNA Sequencing: How to Choose the Right Technology

Introduction It has been over 30 years since the first generation of DNA sequencing technology was developed in 1977. Since […]

Cancer cells take advantage of DNA’s 3D structure

Researchers have explored how cancer cells re-organise the 3D structure of their DNA to enhance oncogene activity. Cancer cells In […]

New DNA modification signature found in zebrafish

Researchers at the Garvan Institute of Medical Research have uncovered a new form of DNA modification in the genome of […]

NSCLC: Implementing ctDNA analysis in the clinic

A recent review, published in Cancers, has summarised the current landscape of ctDNA analysis in clinical practice as well as […]

An overview of alternative biomarkers in liquid biopsy

The most common analytes in liquid biopsies are CTCs and ctDNA. However, there is so much more that can be […]

A guide to liquid biopsy and non-invasive diagnosis

Liquid biopsy offers an innovative solution for the diagnosis and monitoring of cancer and other diseases. However, traditional invasive biopsy […]

An overview of -omics technologies in multi-omics

A multi-omics approach involves the combining of different “omics”: genomics, epigenomics, transcriptomics, and proteomics. The simultaneous study of each “omic” […]

A guide to multi-omics

Multi-omics is the combining of different “omics” – the genome, epigenome, transcriptome and proteome. Studying each layer in isolation can […]

A New Metric for Liquid Biopsies?

In a recent study published in Science, researchers used genome-wide analysis of cell-free DNA (cfDNA) fragment end positions and surrounding […]

A guide to single-cell sequencing and spatial analysis

Introduction The human body contains over 35 trillion cells, with tissues and organs comprising of many different cell types constantly […]