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CRISPR screen unveils the stickiness of T cells

A new study has pinpointed a previously unknown molecular inhibitor of T cell adhesion. The study, published in Science Signalling, […]

Local delivery of anti-CTLA-4 cancer immunotherapy drug is safer than systemic delivery

Results from a clinical trial suggest that local delivery of anti-CTLA-4 immunotherapy drug is safer than systematic delivery. The study, […]

Mosaic loss of Y chromosome leads to increased mortality in aging men

New research using CRISPR-Cas9 has shed light on the condition of mosaic loss of Y chromosome, a previously unexplained risk […]

Genomics week in brief: Week ending 1st July

Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space! Top […]

Rectal cancers disappear in a dostarlimab experimental drug trial

A new drug trial has eliminated 100% of rectal tumours in patients after 6 months. Published in the New England […]

Lupus variants identified with whole-genome sequencing in Chinese patients

A new study has identified key rare variants in systemic lupus erythematosus (SLE) in a Chinese population for the first […]

The abscopal effect and B cells’ surprising role in treating hard to reach tumours

A new study in mice finds that B cells unexpectedly promote the therapeutic shrinking of breast cancer tumours, even when they are not the direct targets of local immunotherapy.  The […]

Tregs: Treacherous cells offer a new therapeutic target in colorectal cancer

Scientists have linked a subset of T cells to the progression of colorectal cancer tumours. Researchers also showed that blocking […]

Spinning a Yarn with the p53 Cancer Protein

Written by Charlotte Harrison, science writer  The tumour suppressor protein p53 is a key controller of cell proliferation. Mutations that […]

Genetic Variants Associated with Severe Covid-19

Written by Vered Smith, Science Writer  Researchers have published a paper revealing genetic variants associated with the development of life-threatening […]