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Can we be genetically predisposed to psychiatric disease and addiction?

A recent study, published in NeuroResource, has used single-nucleus transcriptome analysis to identify cell-type-specific molecular signatures in the brain that […]

Why is understanding cancer evolution so important?

In 1976, Peter Nowell first formally described cancer as an evolutionary process. This was the beginning of the notion that […]

Cancer Genomics: From Diagnosis to Treatment

Introduction The first publication of cancer genome sequencing was in 2006, whereby more than 13,000 genes involved in breast and […]

A guide to spatial transcriptomics

Today, multi-omics studies have been conducted extensively, revealing information about gene expression changes, cellular function and homeostasis. As a result, […]

Multi-omics: Exploring Inside Cells

Introduction Multi-omics is an emerging field. ‘Omics’ refers to the comprehensive collection of a set of biological molecules. Essentially, the […]

Rate of somatic mutations inversely correlates with lifespan

Somatic mutations are implicated in important life processes such as cancer and ageing, yet they still are not well understood. […]

A comprehensive molecular atlas of mouse brain development

By integrating single-cell and spatial transcriptomics technologies, researchers have developed a high-resolution molecular atlas of foetal brain development in mice. […]

Top single cell isolation techniques

Typically, conventional cell-based research focusses on the average response from a population of cells, without taking into account individual cell […]

Sample Preparation for NGS – A Comprehensive Guide

Introduction Sample preparation is the process of getting DNA ready for Next Generation Sequencing (NGS). This requires a few steps… […]

Every Cell Matters: New, Advanced Approaches in High-Throughput Single Cell Sequencing

The adoption of single cell analysis approaches is accelerating, leading to rapid progress in our understanding of complex biological systems. […]