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Polygenic background modifies penetrance of monogenic variants

Researchers have found that polygenic background can modify penetrance of disease in tier 1 genomic conditions. Monogenic variants Monogenic variants […]

Genetics Unzipped podcast: Sickness and susceptibility – the ancient war between genes and disease

Geneticist Dr Kat Arney takes a look at the ancient war between our genes and the pathogens that infect us, […]

Rare TLR7 variants implicated in COVID-19 severity

A study has found that rare genetic alterations in the TLR7 gene may have predisposed two sets of brothers who […]

Genetic risk for Alzheimer’s progression differs with sex

It is well documented that the genetic risk for Alzheimer’s has a sex bias. Sex bias in Alzheimer’s Carrying a […]

Opinion: Do not rely on your genes to fit into your jeans, genetics-based nutrition is risky business!

Recent times has seen an influx in companies offering direct to consumer genetic tests that offer a wide range of […]

Human brain-derived proteome data helps elucidate a genetic causal pathway for neurological phenotypes

A team of researchers have analysed human proteome data from brain tissue to study whether targeted proteins predictively mediated the […]

Largest genetic contributor to height discovered

A team of researchers have identified the largest genetic contributor to height known to date. The gene was found under […]

Opinion: Direct-to-consumer epigenetic tests are not getting enough scrutiny

The direct to consumer (DTC) genetic test market has seen a decline recently over privacy concerns, but private companies such […]

WGS unveils rare structural variants associated with schizophrenia

The genetic basis for schizophrenia has long been studied since the first major study was released over 70 years ago, […]

Genetic map of eight psychiatric disorders released

Around 25% of the world is affected by a psychiatric disorder that can alter their behaviour, social relations and intellectual ability.