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Molecular insight into the cellular immune landscape of psoriatic arthritis

A single-cell sequencing analysis has revealed clonal expansion of pro-inflammatory synovial CD8 T cells in psoriatic arthritis, providing further insight […]

A modern Egyptian: the first comprehensive Egyptian reference genome

The true value of genomics can only be unravelled with true population-scale sequencing. Understanding genomic variation across populations will help […]

Young people can make informed decisions about genome sequencing

A recent study, published in the European Journal of Medical Genetics, has explored the understanding, attitudes and involvement in decision-making […]

The human endometrium at a single-cell level

Researchers have characterised the transcriptomic transformation of the human endometrium during the menstrual cycle at single-cell resolution.  Human endometrium During […]

Mathematical model predicts tumour evolution

Researchers from Barts Cancer Institute and The Institute of Cancer Research (ICR) London have developed a computational model that maps […]

Understanding genetic variation: An integrated personal and population-based Egyptian genome reference

The power of the Human Genome Project was its universality: one genome to represent all humankind. The next challenge is […]

GTEx project sheds light on gene expression

Scientists from the Genotype-Tissue Expression (GTEx) project have completed a range of studies documenting how small changes in the DNA […]

EGFR: Marker for prostate cancer dissemination

Researchers have reported EGFR overexpression as a stable marker for prostate cancer dissemination to rigid organs, preferentially bones. Prostate cancer […]

Genetic modifiers impact long-term survival in sickle cell anaemia

A study published in Clinical and Translational Medicine, has assessed whole-exome sequencing data from sickle cell anaemia patients to identify […]

Differential gene expression analysis reveals new genetic variants implicated in oral cancer

A study published in Scientific Reports, has identified six significant oral cancer associated genes through differential analysis. Oral cancer Oral […]