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Pheno-RNA: a method to associate genes with phenotypes

In a recent article, published in PNAS, researchers have described a new method – Pheno-RNA – to identify candidate genes […]

The Forefront of Genomics

Here we summarise a recent perspective, published in Nature, that has outlined the highest-priority elements in NHGRI’s vision for improving […]

Genomics week in brief: Week ending 7th November

A week filled with election tension and lockdown anger! But here at Front Line Genomics, we have made one thing […]

Round-up: COVID-19 November 2020 (Part One)

With the rising numbers in COVID-19 cases and deaths, the UK has fallen back into a national lockdown – with […]

NSCLC: Implementing ctDNA analysis in the clinic

A recent review, published in Cancers, has summarised the current landscape of ctDNA analysis in clinical practice as well as […]

Off to a catalytic start: Enzymatic DNA synthesis

We all probably remember the enzyme kinetics graphs from school about optimal pH, temperature and substrate concentration in relation to […]

All Wales, All the way!

Megan Fealey, NovaSeq Implementation Lead, and Joseph Halstead, Bioinformatician, from All Wales Medical Genomics Service (AWMGS) joined us to discuss […]

Genetics of penicillin allergy

Researchers have reported the first robust piece of evidence for the role of the major histocompatibility complex (MHC) gene HLA-B […]

Prioritising individuals with disease but low PRS for sequencing

A recent study, published in Genetics in Medicine, has found that prioritising individuals for sequencing who have disease but low […]

Distinct genetic alterations found in African American men with prostate cancer

Researchers have found that prostate cancer tumours from African American men harboured higher frequencies of distinct genetic alterations that may […]