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A guide to spatial transcriptomics

Today, multi-omics studies have been conducted extensively, revealing information about gene expression changes, cellular function and homeostasis. As a result, […]

Choose the right single-cell multi-omics protocol

Single-cell analysis enables deeper characterization of cell populations compared to bulk sequencing, with new experimental methods continuously being developed and […]

Multi-omics: Exploring Inside Cells

Introduction Multi-omics is an emerging field. ‘Omics’ refers to the comprehensive collection of a set of biological molecules. Essentially, the […]

Could Treating Your Microbiome Trigger Healthy Ageing?

The gut microbiome is a significant regulator of the immune system and brain health. As we age, we typically experience […]

New framework links disease SNPs to target genes

A new study has combined SNP-to-gene linking strategies to pinpoint genes that drive disease. The developed framework has identified novel […]

DNA Sequencing: How to Choose the Right Technology

Introduction It has been over 30 years since the first generation of DNA sequencing technology was developed in 1977. Since […]

Modified guide RNAs boost CRISPR-Cas13 transcript knockdown

Researchers at New York University and the New York Genome Center have developed chemically modified guide RNAs that enhance CRISPR-Cas13 […]

Genome Giants – Janet Thornton – Senior Scientist and Director Emeritus at EBI

Dame Janet Thornton is a Senior Scientist and Emeritus Director of EMBL-EBI. Thornton is a pioneer in structural bioinformatics, having […]

A, C, T to Glossary

Numbers The 1000 Genomes Project: The 1,000 Genome Project (1KGP) launched in January 2008 with the aim of generating the […]

Pan-cancer tumour organoids pave the way towards precision medicine

Researchers have developed a platform of pan-cancer tumour organoids and a neural-network-based drug assay, that has the potential to advance […]