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New tool merges single cell RNA-Seq and spatial data

A team has developed a new tool, called cell2location, that can resolve fine-grained cell types in spatial transcriptomic data. Spatial […]

Mitochondrial DNA levels may underlie human diseases

A new study, published in eLife, has identified mitochondrial DNA levels as a potential biomarker of diseases such as cancer […]

Fluctuating methylation clocks can trace cell fates

Researchers have shown that fluctuating DNA methylation sites can be used as ‘clocks’ to trace the lineage of a cell. […]

Generating embryo models from stem cells

A team of researchers have developed a method to generate embryo models from murine stem cells, in the hope of […]

Supermeres: the newly discovered distinct extracellular nanoparticle

Researchers have discovered distinct extracellular nanoparticles, termed supermeres, that have the potential to act as circulating biomarkers and therapeutic targets […]

Sperm cells developed from primate stem cells

With male infertility rates rising globally, researchers have shown for the first time that functional sperm cells can be made […]

How is human pregnancy unique?

In a recent study, researchers delved into the evolutionary history of pregnancy, identifying hundreds of genes that evolved to be […]

Combining single-cell and metagenomics to characterise the microbiome

Metagenomic analysis has greatly advanced our understanding of the human microbiome. However, metagenome-assembled genomes are often imprecise and are unable […]

Exploring Alzheimer’s disease using single-cell/nucleus RNA sequencing data

Scientists have developed a network-based methodology that leverages single-cell/nucleus RNA sequencing data to uncover novel therapeutic targets for Alzheimer’s disease. […]

Genome Giants: Kay Davies – Human Geneticist and Professor of Genetics, University of Oxford

Dame Kay Davies is a human geneticist and Professor of Genetics at the University of Oxford. Davies has spent her […]