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Why do people with Down syndrome develop Alzheimer’s?

For the first time, researchers carried out single-cell transcriptomic analysis and long-read sequencing in Down syndrome brains to better understand […]

New research finds ABI3 gene function in Alzheimer’s disease

Scientists have found that loss of ABI3 function, a protein-coding gene, may increase the risk of developing Alzheimer’s disease by […]

Genomics week in brief: Week ending 30th October

Take a look at some of the latest genomics news and research from the past week in your latest Genomics […]

Understanding prenatal haematopoiesis in bone marrow

Scientists have carried out the first comprehensive analysis of how haematopoiesis develops in prenatal bone marrow. The average human adult […]

Can we be genetically predisposed to psychiatric disease and addiction?

A recent study, published in NeuroResource, has used single-nucleus transcriptome analysis to identify cell-type-specific molecular signatures in the brain that […]

Why is understanding cancer evolution so important?

In 1976, Peter Nowell first formally described cancer as an evolutionary process. This was the beginning of the notion that […]

Cancer Genomics: From Diagnosis to Treatment

Introduction The first publication of cancer genome sequencing was in 2006, whereby more than 13,000 genes involved in breast and […]

A guide to spatial transcriptomics

Today, multi-omics studies have been conducted extensively, revealing information about gene expression changes, cellular function and homeostasis. As a result, […]

Multi-omics: Exploring Inside Cells

Introduction Multi-omics is an emerging field. ‘Omics’ refers to the comprehensive collection of a set of biological molecules. Essentially, the […]

Rate of somatic mutations inversely correlates with lifespan

Somatic mutations are implicated in important life processes such as cancer and ageing, yet they still are not well understood. […]