Complex brain disorders are highly heritable and largely polygenic. They arise from a complex combination of risk genes, found in […]
Epigenetic mechanisms are highly complex, diverse and often poorly understood. A recent study, published in Cell, discusses the diverse features […]
An understanding of the environmental and genetic risk of Alzheimer’s Disease is vital for the production of more effective therapies. […]
In a study, published in Scientific Reports, researchers from the Children’s Hospital of Philadelphia, reported key genetic differences in the […]
As part of the 20th anniversary of Nature Reviews Genetics, Professor Ambroise Wonkam from the University of Cape Town has […]
The power of the Human Genome Project was its universality: one genome to represent all humankind. The next challenge is […]
A study published in Clinical and Translational Medicine, has assessed whole-exome sequencing data from sickle cell anaemia patients to identify […]
A new international consortium of blood genetics has been created by a team at the University of Montreal. Unlike previous […]
Researchers have developed a novel statistical test to interpret the pathogenicity of rare variants and accurately distinguish between benign and […]
Researchers have found that polygenic background can modify penetrance of disease in tier 1 genomic conditions. Monogenic variants Monogenic variants […]
