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Novel applications in single-cell and spatial analysis

In the single-cell and spatial analysis literature you will find hundreds of review articles on these technologies from the past […]

A guide to single-cell sequencing and spatial analysis

Introduction The human body contains over 35 trillion cells, with tissues and organs comprising of many different cell types constantly […]

Choosing single-cell and spatial analysis technologies

The number of different technologies and hardware platforms that are now on the market can be overwhelming. Each comes with […]

An overview of single-cell RNA sequencing and spatial transcriptomics

Single-cell RNA sequencing (scRNA-seq) has become the most established and widely used technique within single-cell analysis. Spatial transcriptomics is quickly […]

Time-restricted feeding impacts gene expression in multiple organs

A recent study has revealed that time-restricted feeding significantly impacts gene expression in mice. The work, published this week in […]

Multimodal tissue characterisation with spatial protein and transcriptome sequencing

A new study, published in Nature Biotechnology, presents Spatial PrOtein and Transcriptome Sequencing (SPOTS) for high throughput combined spatial transcriptomics […]

Social behaviours influenced by genetic and environmental factors

A team of researchers from the University of Utah have discovered that inhibition of the enzyme topoisomerase IIα (Top2a) during […]

Cholesterol dysregulation associated with Alzheimer’s disease

Researchers at the Massachusetts Institute of Technology have uncovered an association between APOE4 and erroneous cholesterol processing. This genetic variant […]

Genetic biomarker profile defined for hard-to-diagnose Lyme disease

Lyme disease is often undiagnosed or misdiagnosed – here we report that there may finally be a genetic biomarker profile […]

Searching in the dark: The role of epigenetics in cancer development

New research, led by scientists at The Institute of Cancer Research, the Human Technopole in Milan, and Queen Mary University […]