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Cancer Genomics: From Diagnosis to Treatment

Introduction The first publication of cancer genome sequencing was in 2006, whereby more than 13,000 genes involved in breast and […]

Distinct DNA methylation sites associated with heart disease

A new study, published in JAMA Cardiology, has identified DNA methylation sites associated with heart disease. Most importantly, the study […]

Multi-omics: Exploring Inside Cells

Introduction Multi-omics is an emerging field. ‘Omics’ refers to the comprehensive collection of a set of biological molecules. Essentially, the […]

Down the Rabbit Hole: Genetics and Obesity – Giles Yeo

Giles Yeo is a Principal Research Associate at MRC Metabolic Diseases Unit and the Scientific Director of the Genomics/Transcriptomics Core […]

A, C, T to Glossary

Numbers The 1000 Genomes Project: The 1,000 Genome Project (1KGP) launched in January 2008 with the aim of generating the […]

Top single cell isolation techniques

Typically, conventional cell-based research focusses on the average response from a population of cells, without taking into account individual cell […]

Twin studies have disentangled the common genes in post-traumatic stress disorder (PTSD) and migraine

A recent study of monozygotic twins revealed certain genes and pathways that overlap between post-traumatic stress disorder (PTSD) and migraine, […]

Cancer cells take advantage of DNA’s 3D structure

Researchers have explored how cancer cells re-organise the 3D structure of their DNA to enhance oncogene activity. Cancer cells In […]

Super-enhancers switch on breast cancer genes

Researchers have identified and characterised a set of specific super-enhancers that stimulate the activity of critical breast cancer genes. Breast […]

Genetic variants impact immune cell function

Researchers have harnessed the power of genome-wide sequencing and functional profiling of immune cells to understand how genetic variants can […]