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Search results for: Polygenic risk score

Down the Rabbit Hole: Genetics and Obesity – Giles Yeo

Giles Yeo is a Principal Research Associate at MRC Metabolic Diseases Unit and the Scientific Director of the Genomics/Transcriptomics Core […]

Precision medicine in early life may improve adult health outcomes

Researchers have shown that optimising early life nutrition can reduce the risk of adult cardiometabolic disease in genetically predisposed infants, […]

Penetrance in monogenic metabolic conditions

Researchers have used exome sequencing data from 77,184 individuals to generate penetrance estimates and assess the utility of polygenic variation […]

The genetics behind eating disorders

An international team has studied the genomes of more than 20,000 individuals, shedding light on the genetic links between eating […]

TWAS: Transcriptome-wide association study

A recent trend in large-scale association studies is transcriptome-wide association study (TWAS), which aggregates genomic information into functionally relevant units […]