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A guide to single-cell sequencing and spatial analysis

Introduction The human body contains over 35 trillion cells, with tissues and organs comprising of many different cell types constantly […]

An overview of single-cell RNA sequencing and spatial transcriptomics

Single-cell RNA sequencing (scRNA-seq) has become the most established and widely used technique within single-cell analysis. Spatial transcriptomics is quickly […]

Microprotein origins contribute to understanding of human evolution

A recent study has revealed several microprotein-encoding genes that have arisen de novo from non-coding sequences within the human genome. […]

Hairpin shaped DNA molecules can selectively kill cancer cells

Researchers have developed a novel approach to target and kill cancer cells. The study, published in the Journal of the […]

Method developed to identify treatment resistant cancer cells in tumours

Researchers have developed a novel way to understand tumour heterogeneity that could be used to prevent cancer relapse. The study, […]

CRISPR technology alters immune cells to fight cancer

Researchers at the University of California, Los Angeles, have combined the use of CRISPR gene therapy with engineered immune cells […]

p53 controls cell metabolism to prevent genomic instability

p53 has long been called the “guardian of the genome,” but how is this tumour suppressor protein maintaining genomic stability […]

Macrophage-targeted CAR T cells offer new hope for cancer therapy

Researchers at the Icahn School of Medicine (Mount Sinai, New York) have found that macrophage-targeted CAR T cells are capable […]

Does the presence of fungi in cancer cells speed up tumour growth?

Written by Aaron Khemchandani, Science Writer. The link between bacteria and cancer has long been evidenced by researchers. Now, however, […]

Single-cell atlas reveals the genes behind exercise-induced weight loss

Written by Lauren Robertson, Science Writer. A new study, published in Cell Metabolism, has revealed the cells, genes and pathways […]