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Search results for: Polygenic Risk Scores

Precision medicine in early life may improve adult health outcomes

Researchers have shown that optimising early life nutrition can reduce the risk of adult cardiometabolic disease in genetically predisposed infants, […]

Penetrance in monogenic metabolic conditions

Researchers have used exome sequencing data from 77,184 individuals to generate penetrance estimates and assess the utility of polygenic variation […]

Phenotype prediction accuracy limited by negative selection

Using population genetic models, researchers show that negative selection on complex traits limits phenotype prediction accuracy between populations. Phenotype prediction […]