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Genetically engineered probiotics

Advancements in the field of synthetic biology, genetic engineering and genome sequencing technologies have provided the opportunity to improve the […]

A year-long human spaceflight reveals circulating biomarkers

A team of researchers have profiled cfDNA isolated from plasma of an astronaut during a year-long mission on the International […]

On the horizon: In situ sequencing

Advancements in technologies, including single cell and spatial transcriptomics, have provided us with a finer view of our complex biology […]

Single cell and spatial technologies

Developments in our technical ability to separate single cells from each other are growing rapidly. Alongside this, sequencing costs are […]

It’s time to talk about epigenetic clocks

Ageing. Mother nature’s curse, but a plastic surgeon’s blessing. All humans age. But how we age and most importantly how […]

On the Cusp of Future Gene Therapies

Gene therapy is at an inflection point. Many gene and cell therapies have been approved in recent years following decades […]

Computational Genetics: A Massive Step for Neuroscience

Complex brain disorders are highly heritable and largely polygenic. They arise from a complex combination of risk genes, found in […]

Circular RNA: Liquid biopsy biomarker for human diseases

A recent review, published in Protein & Cell, has explored the potential use of blood circular RNA as a liquid […]

The Forefront of Genomics

Here we summarise a recent perspective, published in Nature, that has outlined the highest-priority elements in NHGRI’s vision for improving […]

Off to a catalytic start: Enzymatic DNA synthesis

We all probably remember the enzyme kinetics graphs from school about optimal pH, temperature and substrate concentration in relation to […]