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How did Illumina dominate the sequencing market?

Illumina’s systems employ short-read sequencing techniques, which has been the predominant NGS technology for the last decade. The company has […]

Parental genome unification is error-prone

A new study has found that the process of combining maternal and paternal genetic information is surprisingly highly error-prone. Parental […]

The Remarkable Heritability of ACL Injuries

Environmental risk factors associated with ACL injury are generally well known and understood, whereas the genetic basis is still largely […]

Genetic differences in ADHD

In a study, published in Scientific Reports, researchers from the Children’s Hospital of Philadelphia, reported key genetic differences in the […]

Machine learning and Darwin combined to piece together tumour genetics

MOBSTER – model-based clustering in cancer, is a machine learning tool that incorporates theoretical population genetics from Darwin to examine […]

Monocyte gene expression provides insight into depression

A recent paper, published in Translational Psychiatry, uses monocyte gene expression to gain insight into childhood trauma, suicide risk and […]

TISCH: a tumour microenvironment single-cell transcriptomic database

Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]

Biologically-validated AI is how scientists are realising the full potential of single-cell RNA sequencing

The promise of single-cell gene expression data Genomic data are an excellent source of novel disease biomarkers and targets. In […]

Single-cell copy number profiling unveils the genetic diversity of cancer

The genetic information of a cancerous tumour is typically obtained by sequencing the tumour cells together, rather than analysing them […]

Eleven challenges in single-cell data science

Introduction: Single-cell sequencing technology has been advanced by the falling sequencing costs, a boom in microfluidics and combinatorial indexing strategies. […]