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Exploring Alzheimer’s disease using single-cell/nucleus RNA sequencing data

Scientists have developed a network-based methodology that leverages single-cell/nucleus RNA sequencing data to uncover novel therapeutic targets for Alzheimer’s disease. […]

Blood cell ratios correlate with leukaemia risk

A new study, published in the American Journal of Human Genetics, has reported that genetically induced shifts in blood cell […]

Single-cell map explains neuronal death in epilepsy

An interdisciplinary collaboration has deciphered the genomic cellular map associated with hippocampal sclerosis, a major histological condition of temporal lobe […]

Engineered immune cells prevent cancer from spreading

In a recent study in mice, researchers found that engineered immune cells were able to shrink tumours and prevent the […]

CAR-T cell therapy shows promise against rare childhood cancer

A novel CAR-T cell therapy, developed by researchers at UCL and designed to target cancerous tumours, has shown early promising […]

TISCH: a tumour microenvironment single-cell transcriptomic database

Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]

Using large-scale population cohorts to identify novel disease biomarkers

The value of large-scale population cohorts has come to the fore in recent years as these cohorts have matured. They […]

Untangling TKI resistance in lung cancer

Written by Charlotte Harrison, Science Writer Non-small cell lung cancer (NSCLC) is often associated with activating mutations in receptor tyrosine […]

Uncovering Novel MAPK Interactors: A Novel Yeast-based Genetic Screening Platform

In a recent study published in Science, researchers have developed a yeast-based genetic screening pipeline for evaluating large numbers of […]

Proteomics ONLINE

Proteomics is set to play a huge role in the post-genomic era – especially in the context of drug discovery. […]