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5 recommendations for improving rigour and reproducibility in single-cell genomics

An opinion article by Professor Gregory Gibson, Georgia Institute of Technology and director of the Center for Integrative Genomics, offers […]

Combining single-cell and metagenomics to characterise the microbiome

Metagenomic analysis has greatly advanced our understanding of the human microbiome. However, metagenome-assembled genomes are often imprecise and are unable […]

Choose the right single-cell multi-omics protocol

Single-cell analysis enables deeper characterization of cell populations compared to bulk sequencing, with new experimental methods continuously being developed and […]

scCOLOUR-seq: The new method that corrects errors in single-cell sequencing

Researchers have developed a new approach, called single-cell corrected long-read sequencing (scCOLOUR-seq), that is able to amend errors in long-read […]

Single-cell map explains neuronal death in epilepsy

An interdisciplinary collaboration has deciphered the genomic cellular map associated with hippocampal sclerosis, a major histological condition of temporal lobe […]

Mapping the COVID-19 T-cell response at a single-cell level

Understanding COVID-19 immune response While most COVID-19 patients are asymptomatic or display mild symptoms, some patients develop severe clinical symptoms. […]

Single cell analysis provides insight into primary resistance

Using single cell analysis, researchers have revealed cell populations that can predict primary resistance to imatinib in chronic myeloid leukaemia. […]

The human endometrium at a single-cell level

Researchers have characterised the transcriptomic transformation of the human endometrium during the menstrual cycle at single-cell resolution.  Human endometrium During […]

TISCH: a tumour microenvironment single-cell transcriptomic database

Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]

scREAD: single-cell RNA-Seq database for Alzheimer’s Disease

Researchers at The Ohio State University have developed an integrated database known as scREAD – single-cell RNA-Seq database for Alzheimer’s […]