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High-impact variants have been identified in severe schizophrenia

Researchers have employed an extreme phenotype strategy to focus on the most severely affected individuals with schizophrenia and subsequently identified […]

The largest genetic study of suicide attempt identifies genetic underpinnings

In the largest genetic study of suicide attempt to date, researchers have identified a region of the genome containing variants […]

Down the Rabbit Hole: Genomics and Psychedelics – Charles Nichols

Charles Nichols is a Professor of Pharmacology at LSU Health Sciences Centre in New Orleans in USA. His main research […]

Schizophrenia polygenic risk scores: The struggle of improving their clinical utility

Researchers have analysed clinical and genetic data from over 8,500 adults with psychiatric disorders, to assess whether schizophrenia polygenic risk […]

World of Genomics: Germany

In this week’s World of Genomics entry, we explore Deutschland, also known more commonly as Germany. Despite the strength of […]

Multi-omics integration analysis uncovers genes driving alcoholism

A new study, published in Nature Communications, has used a multi-omics systems approach to identify genes underlying alcohol use disorders. […]

Twin studies have disentangled the common genes in post-traumatic stress disorder (PTSD) and migraine

A recent study of monozygotic twins revealed certain genes and pathways that overlap between post-traumatic stress disorder (PTSD) and migraine, […]

Obsessive-compulsive disorder (OCD) has been linked to genetic mutations

A genome-wide study has identified potential risk genes that are associated with obsessive-compulsive disorder (OCD), confirming the validity of using […]

White matter microstructure in the brain is influenced by genetic variants

Recently, a genome-wide association study has identified genetic variants that influence white matter microstructure in the brain. White matter was […]

GWAS of bipolar disorder provides new insights

A new genome-wide association study (GWAS) of over 40,000 bipolar disorder cases has provided new insights into the underlying disease […]