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Advanced Research Models ONLINE

We frequently read articles about how diseases have been reversed, halted and cured in mice, yet effective treatments for humans […]

Genomics week in brief: Week ending 4th March

Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space! Top […]

New rare disease discovery sheds light on cellular recycling process

Scientists from the NIH’s National Human Genome Research Institute (NHGRI) and Undiagnosed Diseases Program (UDP) have identified a new rare […]

Comprehensive sequencing of the small intestine reveals “collateral damage” by APOBEC1 enzyme may lead to cancer

Researchers at the Wellcome Sanger Institute have found that the enzyme APOBEC1 may cause the mutations SBS2 and SBS13 – […]

A guide to single-cell sequencing and spatial analysis

Introduction The human body contains over 35 trillion cells, with tissues and organs comprising of many different cell types constantly […]

An overview of single-cell and spatial proteomics

The majority of single-cell analysis studies focus on nucleic acids. The central dogma of molecular biology states that DNA is […]

A neuroprotective bacterium for ALS identified

Researchers have investigated the neuroprotective capacity of probiotics. The study, published in Communications Biology, identified a probiotic bacterium that protects […]

Virus-derived CRISPR systems may be added to the gene-editing toolbox

The CRISPR-Cas9 system revolutionised genome editing approaches. Recent work on the CRISPR gene editing technology won the 2020 Nobel Prize […]

Cancer clone maps provide direction on breast cancer metastasis

There are around 55,900 new breast cancer cases in the UK every year – more than 150 cases every day. […]

The Magnificent Microbiome: Where have we been and where are we going? (Part 1)

In this blog, we will attempt to cover some of the many ways our microbiomes impact our health and wider […]