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Sequencing of adult cells provides insight into human embryogenesis

How the human embryo develops is a complex and unclear phenomenon. Scientists are faced with many challenges when it comes […]

A single-cell atlas of human teeth

Using advanced single-cell sequencing technologies, a team of researchers have generated the first ever single cell atlas of human teeth. […]

The human endometrium at a single-cell level

Researchers have characterised the transcriptomic transformation of the human endometrium during the menstrual cycle at single-cell resolution.  Human endometrium During […]

FoG 2020 Presentation Andrew Bassett, Wellcome Sanger: Editing the genome of human iPS cells

Andrew leads the Human Gene Editing R&D group at the Wellcome Sanger Institute.  After obtaining his PhD at the MRC-LMB […]

New Commercial Developments in Single-cell Sequencing

This feature on single-cell sequencing technology is adapted from parts of Chapters 1 & 2 of the upcoming Spatial and […]

Key cross-species genes offer insight into human bladder cancer development

Muscle invasive bladder cancer (MIBC) is an aggressive form of human bladder cancer. Little is currently known about the genetic […]

This cell will self-destruct in 5 days

‘This cell will self-destruct in 5 days’ – Written by Charlotte Harrison, Science Writer. A team of researchers have used […]

Capturing the complexity of single-cell interactions

‘Capturing the complexity of single-cell interactions’ – Written by Charlotte Harrison, Science Writer. Single-cell and spatial genomics approaches generate high-dimensional […]

The human lung mapped in unprecedented detail

The most comprehensive cellular map of the human lung has been published in Nature Medicine. It is part of the […]

Transcriptome and circular DNA sequencing in single cancer cells

A new single-cell sequencing method has been published in Nature Genetics. Single-cell extrachromosomal circular DNA and transcriptome sequencing (scEC&T-seq) can […]