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Studies find CRISPR gene-editing of human embryos give rise to unwanted results.

CRISPR gene-editing is a technique that allows the genomes of living organisms to be modified. Naturally, this has been looked […]

RNA Editing: The New CRISPR?

RNA therapeutics have gained traction over the last four years, not least because of the significant global effort to create […]

Back to Basics – Base & Prime Editing

In our most recent Back to Basics feature, we took a look at CRISPR, the gene editing technique that took […]

Base and Prime Genome Editing in Precision Oncology

This feature on prime and base editing is adapted from content provided in the Cancer Genomics 2023 Report. The introduction […]

A new role for RNA editing in immune-cell trafficking

Written by Charlotte Harrison, Science Writer A paper published in the journal Immunity has identified a new role for the […]

Prime editing successfully corrects sickle cell mutation

Researchers have used prime editing to correct the mutation that causes sickle cell disease in patient-derived stem cells. The study, […]

CRISPR editing in the lung

Written by Charlotte Harrison, Science Writer Delivering gene therapies to the lung is challenging because of its specialized cell types […]

Base editing successfully corrects immune deficiency mutation

Researchers have used base editing to correct the mutation that causes a rare immune disorder. A one-off gene therapy could […]

Gene expression changes contribute to Type 2 diabetes disease pathology

A study, recently published in the Journal of Clinical Investigation, has revealed nearly 400 genes that are expressed differentially in […]

Say Goodbye to Trial and Error: New Machine Learning Tool Improves Efficiency of Prime Editing

In a recent paper, published in Nature Biotechnology, scientists at the Wellcome Sanger Institute have developed a machine learning tool […]