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Studies find CRISPR gene-editing of human embryos give rise to unwanted results.

CRISPR gene-editing is a technique that allows the genomes of living organisms to be modified. Naturally, this has been looked […]

A new role for RNA editing in immune-cell trafficking

Written by Charlotte Harrison, Science Writer A paper published in the journal Immunity has identified a new role for the […]

Prime editing successfully corrects sickle cell mutation

Researchers have used prime editing to correct the mutation that causes sickle cell disease in patient-derived stem cells. The study, […]

CRISPR editing in the lung

Written by Charlotte Harrison, Science Writer Delivering gene therapies to the lung is challenging because of its specialized cell types […]

Base editing successfully corrects immune deficiency mutation

Researchers have used base editing to correct the mutation that causes a rare immune disorder. A one-off gene therapy could […]

Gene expression changes contribute to Type 2 diabetes disease pathology

A study, recently published in the Journal of Clinical Investigation, has revealed nearly 400 genes that are expressed differentially in […]

Say Goodbye to Trial and Error: New Machine Learning Tool Improves Efficiency of Prime Editing

In a recent paper, published in Nature Biotechnology, scientists at the Wellcome Sanger Institute have developed a machine learning tool […]

Researchers Investigate the Epigenetic Regulation of NRG1 in Breast Cancer Under Hyperglycaemia

In a new study published in Nature, researchers investigated the molecular mechanisms behind the epigenetic regulation of the NRG1 enhancer […]

Predictive models could identify oncogenic genetic events

Researchers have shown that some cancer-causing genetic events are underpinned by regulatory gene activity. The study, published in Nature, highlights […]

Gene therapy for neurological diseases possible with new brain-targeting viral vectors

A major challenge in the field of gene therapy is ensuring that treatments are delivered to the correct location in […]