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How to do RNA sequencing

RNA sequencing is an NGS technique that enables investigation of the transcriptome – the total cellular content of RNAs, including […]

Long-read sequencing vs short-read sequencing

Different sequencing platforms use a variety of read lengths. Both short-read sequencing and long-read sequencing have their own benefits and […]

The progress of NGS platforms

It has been over 30 years since the first generation of DNA sequencing technology was developed in 1977. Since then, […]

Sample Preparation for NGS – A Comprehensive Guide

Introduction Sample preparation is the process of getting DNA ready for Next Generation Sequencing (NGS). This requires a few steps… […]

AlphaFold 2 open up protein structure prediction software for all

Source code for AlphaFold 2, an algorithm that predicts 3D protein structure with unprecedented accuracy, is now freely available. Proteins […]

Envisioning a CRISPR/Cas9-based therapy for retinitis pigmentosa

A proof-of-principle study has shown that template-free CRISPR/Cas9 gene editing can correct mutations that cause X-linked retinitis pigmentosa in mouse […]

Differential DNA methylation contributes to risk of multiple sclerosis

A recent study has discovered differentially methylated genomic regions harbouring 4 loci associated with risk of multiple sclerosis. Multiple sclerosis […]

How to: generate mouse-human chimeric embryos

A recent article published in Nature Protocols has detailed a breakthrough approach in generating mouse-human chimeric embryos with human pluripotent […]

Round-up: COVID-19 July 2021 (Part One)

We have got you covered with all of the latest news and research surrounding the novel coronavirus pandemic from the […]

Laminins could hold the key for novel anticancer strategies

A recent study has uncovered that a group of glycoproteins, called laminins, are essential for fighting and killing cancer cells, […]