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Proteogenomics provides insight into head and neck cancer

A study using proteogenomics has offered new insight into matching cancer patients with an effective therapy for their particular cancer. […]

Study redefines S-phase checkpoint

A recent study, published in eLife, has redefined our understanding of the S-phase checkpoint which has important implications for our […]

Chromothripsis: A driver of gene amplification in cancer

Researchers have used whole-genome sequencing (WGS) to show that chromothripsis is a major driver of circular extrachromosomal DNA amplification. Gene […]

Treating Cystic Fibrosis: To Splice or Not to Splice?

Cystic Fibrosis Cystic Fibrosis (CF) is an autosomal recessive genetic disorder, caused by the dysfunction of the CF transmembrane conductance […]

Genome-wide Screens Identify Genes that Dampen Immunosurveillance in Cancer

Tumours often avoid detection by CD8+ T cells through disrupting peptide presentation by major histocompatibility complex class I (MHC-I). However, […]

Single cell analysis provides insight into primary resistance

Using single cell analysis, researchers have revealed cell populations that can predict primary resistance to imatinib in chronic myeloid leukaemia. […]

The Association for Molecular Pathology Annual Meeting

We attended this year’s annual meeting of The Association for Molecular Pathology. It was a virtual meeting that took place […]

CRISPR system destroys cancer cells

Researchers have utilised lipid nanoparticles to deliver CRISPR technology and found that this technology could destroy cancer cells within an […]

Round-up: COVID-19 November 2020 (Part Two)

Despite the rise in COVID-19 cases and deaths, hopes for a vaccine have become more of a reality. Here, we […]

Lung microbiome implicated in lung cancer pathogenesis and prognosis

A recent paper, published in Cancer Discovery, has found that enrichment of the lungs with oral commensal microbes was associated […]