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JAG2 Mutation – New cause for Muscular Dystrophy

A mutation in a previously unexamined Notch ligand, JAG2, is found to cause a rare form of muscular dystrophy (MD) […]

CRISPR identifies gene involved in metastasis

New research from scientists at the Wellcome Sanger Institute has revealed a gene that plays a key role in metastasis […]

A new player in graft-versus-host disease

Researchers have identified a long noncoding RNA whose function has shown to play a key role in graft-versus-host disease and […]

The diversity of cancer targets

Here we summarise a recent paper, published in Cell, that explored the landscape of therapeutic cancer targets beyond the list […]

Combination therapy for mitochondrial disorders

Study shows how one specific combination therapy may provide measurable benefits to patients with mitochondrial respiratory chain disorders. Mitochondrial disorders […]

Large study reveals 127 glaucoma genes

In the largest genome-wide association study of glaucoma, an international consortium of researchers has identified 44 new gene loci and […]

Blood cancers originate decades before diagnosis

Researchers at Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and EMBL-EBI have reconstructed the lineage history of individual hematopoietic stem […]

Gene impacts the timing of labour

A new study has demonstrated how a gene called HAND2 can play a role in the timing of labour. The […]

Uninherited mutations in spina bifida

Researchers have found that uninherited mutations that occur randomly during the earliest stages of embryonic development can cause spina bifida. […]

Colon cancer transformation revealed

Researchers from Max Planck and their collaborators have revealed the transformation of colon organoids in vitro. Colorectal cancer Colorectal cancer […]