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Super-enhancers switch on breast cancer genes

Researchers have identified and characterised a set of specific super-enhancers that stimulate the activity of critical breast cancer genes. Breast […]

CRISPR identifies gene involved in metastasis

New research from scientists at the Wellcome Sanger Institute has revealed a gene that plays a key role in metastasis […]

A new player in graft-versus-host disease

Researchers have identified a long noncoding RNA whose function has shown to play a key role in graft-versus-host disease and […]

New insights into X-inactivation

Researchers at Massachusetts General Hospital have uncovered new insights into our understanding of X-inactivation in female mammals. Chromosome architecture Classical […]

ADAR1 protects telomeres and supports cancer cell proliferation

Researchers at The Wistar Institute have identified a new function of ADAR1, a protein responsible for RNA editing, discovering that […]

Protein architecture of budding yeast

Researchers have mapped the binding locations of over 400 different proteins on the yeast genome, providing the most thorough and […]

Induced pluripotent stem cells map variants of disease

Scientists have compiled data from induced pluripotent stem cells to link genetic variants to many different diseases. Linking variants Researchers […]

3D Genetics, EpiSwitch™️ and Clinical Translation: Development of Liquid Biopsy for Diffuse large B-cell lymphoma prognosis and benchmarking it against digital PCR gold standards

Chromatin exists as a non-linear, “three-dimensional” structure in the nuclear space, and refers to the complex of DNA and proteins […]

Fuelling the Century of Biology with Single Cell and Spatial Technologies

With developments in our ability to separate single cells from each other and the falling costs of sequencing, single cell […]

Hallmarks of environmental insults

We summarise a recent paper, published in Cell, that has proposed eight hallmarks of environmental insults. The intricacies and interactions […]