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Treating Cystic Fibrosis: To Splice or Not to Splice?

Cystic Fibrosis Cystic Fibrosis (CF) is an autosomal recessive genetic disorder, caused by the dysfunction of the CF transmembrane conductance […]

12 Days of Genomics Christmas

Here at Front Line Genomics, we thought we would spread some Christmas cheer with the 12 days of Christmas but […]

Gene therapy in sickle cell disease patients

A team at Boston Children’s Hospital have reported on the success of their virus gene therapy in six sickle cell […]

CRISPR system destroys cancer cells

Researchers have utilised lipid nanoparticles to deliver CRISPR technology and found that this technology could destroy cancer cells within an […]

On the horizon: In situ sequencing

Advancements in technologies, including single cell and spatial transcriptomics, have provided us with a finer view of our complex biology […]

Circular RNA: Liquid biopsy biomarker for human diseases

A recent review, published in Protein & Cell, has explored the potential use of blood circular RNA as a liquid […]

Transposon expression impacts neuronal function

Research at the University of Oxford has revealed that transposon expression within the brain is not random and is in […]

Novel circRNA identified as a potential biomarker for pancreatic cancer

A recent study, published in the Journal of Human Genetics, has analysed and identified a novel circRNA in pancreatic cancer […]

Just one base at a time

The advancements in base editing, a new genome editing approach, have generated a lot of excitement amongst scientists in recent […]

Fast and Furious: A race to develop a vaccine

The development of a COVID-19 vaccine is critical to slow down the spread of the virus. However, the rapid race […]