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Exploring kinase fusions in lung cancer

A group of Chinese researchers have extensively studied kinase fusions in lung cancer, in the hope of providing valuable evidence […]

Researchers identify a genetic cause of endometriosis

Endometriosis affects 1 in 10 women worldwide. The current therapies for this condition are limited and tend to focus on […]

Investigating persister cells in lung cancer

Persister cells in cancerous tumours are a major contributor to treatment resistance. Unfortunately, these rare cells are not well understood. […]

Inhibition of protein reverses hallmark of motor neurone disease

A new study, led by scientists at UCL and the Francis Crick Institute, has found that the inhibition of an […]

New framework links disease SNPs to target genes

A new study has combined SNP-to-gene linking strategies to pinpoint genes that drive disease. The developed framework has identified novel […]

A new strategy to combat solid tumours with neoantigen-based immunotherapy

A preclinical study has provided in vitro and in vivo evidence for using mutated KRAS epitopes as a viable target […]

A brief history of Next Generation Sequencing (NGS)

Since the discovery of the basic double-helix structure of DNA In the 1950’s, scientists have devoted a huge amount of […]

Gene therapy reverses age-related memory impairment

Researchers have developed a new strategy to rescue age-related memory impairment in mice with gene therapy, which involves restoring the […]

Macropinocytosis: how cancer cells survive

Researchers have revealed a novel process by which cancer cells can repair fatal membrane injuries by macropinocytosis. Repairing plasma membrane […]

How to: generate mouse-human chimeric embryos

A recent article published in Nature Protocols has detailed a breakthrough approach in generating mouse-human chimeric embryos with human pluripotent […]