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A novel pathway in the pathology of Rett syndrome

Researchers have revealed how dysregulation of the MECP2/miR-199a axis may contribute to the molecular pathology of Rett syndrome. Rett syndrome […]

Whole-exome sequencing and the potential for obesity treatment

Researchers have demonstrated the potential of large-scale whole-exome sequencing in facilitating therapeutic target discovery to combat obesity. The recent upsurge […]

Twin studies have disentangled the common genes in post-traumatic stress disorder (PTSD) and migraine

A recent study of monozygotic twins revealed certain genes and pathways that overlap between post-traumatic stress disorder (PTSD) and migraine, […]

The functional importance of unusual DNA structures called G4s has been revealed

For the first time, researchers have found that G-quadruplex structures (G4s) in DNA could be added to the list of […]

HLA-DR4: The human antigen with subtypes that are strongly linked to type 1 diabetes

Researchers have identified three amino acid residues that are responsible for the variable association of HLA-DR4 subtypes with type 1 […]

White matter microstructure in the brain is influenced by genetic variants

Recently, a genome-wide association study has identified genetic variants that influence white matter microstructure in the brain. White matter was […]

Multi-Omics ONLINE – July Series

Sequencing technologies are continuously improving, making it easier to obtain more in-depth molecular information than ever before. As such, we […]

The effects of DNA methylation on 3D structure

Researchers have explored how methylation patterns have a protein-independent regulatory role that increases the stiffness of DNA, which ultimately impacts […]

Reimagine neuroscience with single cell and spatial multiomics

The nervous system is a complex system made up of a plethora of cell types. Neurological disorders represent a leading cause […]

A cellular culprit for type 1 diabetes

By harnessing various genetic tools, researchers have identified a predictive causal role for specific cell types in type 1 diabetes. […]