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Genomics week in brief: Week ending 8th January

Below, we have summarised the latest news and research in the genomics space from the past week.

Top stories from the past week

  • Researchers have developed the first non-muscle targeted gene therapy that can restore the ability of injured muscle fibers to repair and improve muscle function. (Bittel et al, 2022)
  • A new study has demonstrated a link between brain chemical, GABA, and visual processing in autism. (Huang et al, 2022)
  • Researchers have shown for the first time that the DNA methylome of glioblastomas can be reprogrammed using high dose L-methylfolate alongside standard therapy. (Salas et al, 2022)
  • A recent analysis has revealed that the shapes of fingerprints are influenced by genes linked to limb development. (Li et al, 2022)
  • A large study has identified molecular signatures of gestational inflammation that are linked to the risk of developing autism spectrum disorder. (Che et al, 2022)
  • Researchers have refined retrons to be optimised for editing genes from a variety of cell types. (Lopez et al, 2022)
  • A new study has shown that the third copy of chromosome 21 in Down syndrome cells causes genome-wide disruptions that mimic a senescence-like state. (Meharena et al, 2022)
  • Scientists have found that a vaccine-like injection of mRNA can be used to make CAR-T cells in the body. (Rurik et al, 2022)

In other news

  • Singapore researchers have been awarded the prestigious Wellcome Leap R3 Programme contract to develop the next generation of mRNA technology. (GEN, 2022)
  • Pfizer and BioNTech have signed a new global collaboration agreement to develop the first mRNA-based shingles vaccine. (Pfizer, 2022)

Image credit: canva