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Genomics week in brief: Week ending 6th March

Another month, another genomics week in brief – filled with the latest research and news surrounding genomics.

Top stories from the past week

  • Researchers have developed a new single-cell transcriptomics method – MutaSeq – that can distinguish cancer stem cells, mature cancer cells and otherwise healthy stem cells based on their genetics and gene expression. (Steinmetz et al, 2021)
  • A study has proposed a new, non-invasive way to test for transplant rejection using exosomes from urine samples. (Azzi et al, 2021)
  • Researchers have uncovered a new molecular driver of frontal circuit maturation and demonstrated that this mechanism can be targeted to restore attention deficits caused by a leading genetic cause of autism. (Falk et al, 2021)
  • A new study has described the success of individualised brain cell grafts reversing Parkinson’s symptoms in monkeys. (Zhang et al, 2021)
  • Princeton researchers have completed the first comprehensive analysis of cancer-associated histone mutations in the human genome. (Muir et al, 2021)
  • An international team of researchers has, for the first time, detected genetic variants that could provide clues as to how keratoconus develops. (Hardcastle et al, 2021)
  • New findings have provided insights into tuneable drug delivery and new design paradigms of DNA-based drug-carriers. Here, researchers observed an anti-cancer drug release from DNA nanostructures in real time. (Linko et al, 2021)
  • New research has shed light on how the immune system develops during infancy, showing a causal relationship between neonatal antibody production and the mother’s microbiota. (Mu et al, 2021)
  • Researchers have discovered that mitochondrial DNA acts as a danger signal in the body and triggers inflammation in people with sickle cell disease. (Thein et al, 2021)

In other news

  • A small sensor used in brain chemistry research can detect genetic material and be used to conduct precise measurement of chemicals in the brain. (Zestos et al, 2021)

Events

  • Join us for our brand new three-part webinar series – ‘Next-Gen PCR ONLINE’ . In this series, we highlight how next-gen PCR methods can impact modern science. The first webinar is taking place on Thursday 11th March at 3PM GMT/4PM CET/10AM EST. Register now.
  • Catch up on our latest webinar series – ‘Microbiome Sequencing ONLINE‘. In this series, we explored how metagenomics and microbiome sequencing is uncovering the hidden traits of the invisible world. To watch the webinars on-demand register now.

Reports

  • Download our latest report: ‘Liquid Biopsy: Current Status and Future Directions’. This report will provide you with an overview of liquid biopsy technologies, exclusive interviews with key leaders in the field and insights into the current technical and social barriers impacting clinical uptake. Get your free copy here.

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