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Genomics week in brief: Week ending 6th March

Another month, another genomics week in brief – filled with the latest research and news surrounding genomics.

Top stories from the past week

  • Researchers have developed a new single-cell transcriptomics method – MutaSeq – that can distinguish cancer stem cells, mature cancer cells and otherwise healthy stem cells based on their genetics and gene expression. (Steinmetz et al, 2021)
  • A study has proposed a new, non-invasive way to test for transplant rejection using exosomes from urine samples. (Azzi et al, 2021)
  • Researchers have uncovered a new molecular driver of frontal circuit maturation and demonstrated that this mechanism can be targeted to restore attention deficits caused by a leading genetic cause of autism. (Falk et al, 2021)
  • A new study has described the success of individualised brain cell grafts reversing Parkinson’s symptoms in monkeys. (Zhang et al, 2021)
  • Princeton researchers have completed the first comprehensive analysis of cancer-associated histone mutations in the human genome. (Muir et al, 2021)
  • An international team of researchers has, for the first time, detected genetic variants that could provide clues as to how keratoconus develops. (Hardcastle et al, 2021)
  • New findings have provided insights into tuneable drug delivery and new design paradigms of DNA-based drug-carriers. Here, researchers observed an anti-cancer drug release from DNA nanostructures in real time. (Linko et al, 2021)
  • New research has shed light on how the immune system develops during infancy, showing a causal relationship between neonatal antibody production and the mother’s microbiota. (Mu et al, 2021)
  • Researchers have discovered that mitochondrial DNA acts as a danger signal in the body and triggers inflammation in people with sickle cell disease. (Thein et al, 2021)

In other news

  • A small sensor used in brain chemistry research can detect genetic material and be used to conduct precise measurement of chemicals in the brain. (Zestos et al, 2021)


  • Join us for our brand new three-part webinar series – ‘Next-Gen PCR ONLINE’ . In this series, we highlight how next-gen PCR methods can impact modern science. The first webinar is taking place on Thursday 11th March at 3PM GMT/4PM CET/10AM EST. Register now.
  • Catch up on our latest webinar series – ‘Microbiome Sequencing ONLINE‘. In this series, we explored how metagenomics and microbiome sequencing is uncovering the hidden traits of the invisible world. To watch the webinars on-demand register now.