Christmas is fast approaching and here at Front Line Genomics we have a gift for you – the latest genomics research and news all in one place!
Top stories from the past week
- New findings have revealed that women face a 20% increased risk of developing heart failure or dying within five years after their first severe heart attack compared to men. (Ezekowitz et al, 2020)
- A new study has provided insight into how reprogrammed mesenchymal stem/stromal cells are regulated molecularly to enhance the cellular hallmarks of ageing. (Li et al, 2020)
- An epigenome-wide meta-analysis of DNA methylation differences in the prefrontal cortex, has implicated immune processes in Alzheimer’s disease pathology. (Wang et al, 2020)
- A recent article has documented the use of CRISPR tagging for making adult neuronal cells – a technique that could be applied to any cell type. (Gersbach et al, 2020)
- Researchers have developed a comprehensive library of the programming landscape mediated by transcription factors known as the Human TFome. (Church et al, 2020)
- POEMS syndrome is a rare plasma cell dyscrasia. Using whole exome sequencing, researchers have uncovered the heterogenous genomic profile of bone marrow plasma cells in POEMS syndrome. (Li et al, 2020)
- Researchers have reported HDAC7 as an important contributor to the pathogenesis of t(4;11) leukaemia. The identification of HDAC7 as a clinical prognostic marker for t(4;11) leukaemia opens up new therapeutic avenues. (Parra et al, 2020)
- New findings have revealed the molecular characteristics of KEAP1 and TSK11 driven lung adenocarcinomas, showing that they block a type of cell death called ferroptosis. These findings highlight a promising candidate for targeted drug development. (Rudin et al, 2020)
- Researchers from the University of Sheffield have identified a new genetic risk factor for motor neurone disease. (Shaw et al, 2020)
- Harvard Medical School scientists have successfully restored vision in mice by turning back the clock on aged eye cells in the retina. (Sinclair et al, 2020)
Events
- It’s back!!! Registration for the Festival of Genomics & Biodata 2021 is now open – so grab yourself a ticket and join us for an event you won’t forget! With a host of amazing speakers and cutting-edge content this event will be sure to make your January a lot brighter! Register now.
- Catch up on demand with our recent ‘Single Cell ONLINE’ webinar series, where we delved further into the technology that is giving insights into cellular heterogeneity.
Reports
- Download your free copy of our report – ‘Biology at High Resolution – Advances in Single Cell Analysis: A Review’. The report includes lessons learned from global researchers, discussions about the clinical applicability of single cell analysis and some exciting insights into how single cell analysis is being delivered. Download now.
- Download our free guide – ‘Sample Preparation Guide for MPS’ – which covers everything you need to know about sample preparation. Written by Professor David Smith (Mayo Clinic), this report will help you start your genomics workflow right! Download the report now.
