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Genomics week in brief: Week ending 29th May

Check out our summary of all of the most recent genomics news and research from the past week!

Top stories from the past week

  • Scientists have discovered how the high-risk gene for developing autism spectrum disorder (Cullin 3) affects brain development. (Morandell et al, 2021)
  • A new research study has found that telomeres shorten most rapidly during early childhood. (Cowell et al, 2021)
  • Researchers have identified a way of reactivating ‘paralysed’ immune cells to fight against brain tumours. (Platten et al, 2021)
  • A new study has explored the effectiveness of CAR T-cell therapies in children with leukaemia, identifying a small subset of T-cells that are likely to play a key role in therapy success. (Biasco et al, 2021)
  • A multidisciplinary team has developed a new software tool (CRISPECTOR) to detect, evaluate and quantify off-target editing activity of CRISPR-Cas9 technology. (Amit et al, 2021)
  • University of Virginia School of Medicine scientists have developed a new computational method to map the folding patterns of chromosomes in three dimensions. This tool will help develop better ways to treat and prevent cancer.  (Thomas, Wang and Zang, 2021)
  • Using proteomics technology, researchers have revealed how exercise increases the efficiency of muscle energy production. (Gonzalez-Franquesa et al, 2021)
  • A new study had overturned the long-held belief that T cells can perfectly distinguish between healthy and infected cells. (Pettmann et al, 2021)
  • Researchers have identified many new genetic variants that increase the risk of depression in the largest genetic analysis of depression to date. (Levey et al, 2021)
  • A recent analysis has explored the importance of transparency regarding data use across 22 different countries. (Milne et al, 2021)
  • A new study has provided important information about how DNA variants can suppress undesirable genetic changes. (Parts et al, 2021)
  • A University of Idaho-led study has found that there is ongoing evolution in Tasmanian Devils’ response to transmissible cancer. (Stahlke et al, 2021)


  • Make sure you catch up on our latest series – ‘Genomics in Drug Discovery & Development’. In this series, we delved into how genetics and genomics is being used to improve modern drug discovery.
  • Join us on Thursday 3rd June at 3pm BST/4pm CEST/10am EDT for a webinar titled: ‘Applying Personalized Genomics to Ash Trees’. In this webinar, Professor Richard Buggs (Royal Botanical Gardens, Kew) presents a case study focussing on the genomics of tree health and adaptation.

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Genomics / Immune System / Week in brief