A lot can happen in a week! But don’t worry we’ve got you covered with the latest round-up of the top genomics news and research from the past week.
Top stories from the past week
- Bioengineered models have allowed researchers to regenerate and study living patient-specific skin, providing insight into how DNA defects in children can cause cancer. (Wells et al, 2020)
- New research has found that reprogramming immune-system T cells into regenerative stem cell-like memory cells can improve T cell therapies for cancer patients. (Khleif et al, 2020)
- Researchers have studied the incidence and regional distribution of Alzheimer’s disease biomarkers in the brains of individuals with Down Syndrome. (Lemoine et al, 2020)
- New findings indicate that BASP1 is a pharmacologically relevant receptor for cocaine and a potential therapeutic target for psychostimulant addiction. (Harraz et al, 2020)
- Researchers find that common diseases can alter the physiological age-related blood microRNA profile. (Keller et al, 2020)
- A team of researchers have used biobank-scale pharmacogenomics to inform the genetic underpinnings of simvastatin use. (Wendt et al, 2020)
- Scientists have developed a lung-on-a-chip model to study how the body responds to early tuberculosis infection. (Thacker et al, 2020)
- Using a variety of advanced drug screening techniques, researchers have found that the widely used antibiotic methacycline was effective at preventing brain infections and reducing neurological problems associated with Zika virus in mice. (Nath et al, 2020)
- Scientists from Trinity College Dublin have developed a new gene therapy approach that offers promise for one day treating an eye disease that causes progressive vision loss and affects thousands of people globally. (Farrar et al, 2020)
- A meta-analysis of up to ~1.3 million participants has found rare variants associated with blood pressure regulation. (Howson et al, 2020)
- New research sheds light on how CRISPR-Cas emerged early during the development of life on Earth as well as how this immune system is constantly adapting to new challenges. (Brodersen et al, 2020)
- A proteomic screen in mice has provided insight into the effects of endosomal trafficking alterations in Alzheimer’s disease. (Simoes et al, 2020)
- Hi-C analysis shows that oncogenic RAS-induced senescence in human cells is accompanied by extensive enhancer-promoter rewiring, which is closely linked with dynamic cohesin binding. (Narita et al, 2020)
In other news
- A study by Queen Mary University of London has shown that mammography screening continues to play an important role in lowering the risk of dying from breast cancer. (Duffy et al, 2020)
- The NHS are set to pilot a new blood test developed by GRAIL which can detect more than 50 types of cancer. (NHS England, 2020)
Events
- Join us this week for the final webinar in our ‘Single Cell ONLINE’ webinar series this Thursday (3rd December). In this webinar, we will be exploring the use of single cell analysis for genetic risk studies. Register now.
Reports
- Download our free guide – ‘Sample Preparation Guide for MPS’ – which covers everything you need to know about sample preparation. Written by Professor David Smith (Mayo Clinic), this report will help you start your genomics workflow right! Download the report now.
- Check out our report – ‘Biology at High Resolution – Advances in Single Cell Analysis: A Review’. The report explores lessons learned from global researchers and discusses the clinical applicability of single cell analysis. Download the report now.
