Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space!
Top stories from the past week
- This week, gene therapy effectively treated advanced-stage muscular dystrophy in a mouse model. (Yonekawa et al)
- A new study of samples from patients with inherited acidemia leads to an experimental gene therapy. (Head et al)
- Researchers have shed light on potentially bioactive gene products in inflammatory bowel diseases, offering therapeutic targets. (Zhang et al)
- Within a special issue on the multiplicity of microbiomes, a review considers how “omics” research has expanded our knowledge of how a host’s tissues and microbiota interact. (Lu & Stappenbeck)
- Researchers from Lanzhou University Secondary Hospital identify a potential therapeutic target for diffuse-type gastric cancer. (Qin et al)
- A new study investigated synthetic gene circuits and how they could prevent the disruption of the circadian rhythm in cartilage. (Pferdehirt et al)
- A team of researchers demonstrated that PACT plays a key role in regulating mitochondrial biogenesis and energetics in cell. (Dogan et al)
- French researchers present T cell immunogenicity and gene expression profiles from the results of a HIV vaccine trial in healthy volunteers. (Richert et al)
- A new study identified an RNA-editing enzyme as masking the cancer immunotherapeutic promise of ZBP1-driven necroptosis. (Zhang et al)
- Scientists have defined mitochondrial protein functions through deep multiomic profiling. (Rensvold et al)
- Through bioinformatic prospecting, researchers discovered and synthesized a novel, naturally inspired bifunctional lipopeptide antibiotic with a low resistance potential. (Seipke)
- Using RNA sequencing, a new study has shown that transcriptional regulators can substantially alter disorder outcome, implicating them as therapeutic targets. (Burda et al)
- A new study connects genomics and proteomics to identify protein biomarkers for adult and youth-onset type 2 diabetes. (Ghanbari et al)
In other news:
- Pompeii victim’s genome successfully sequenced for first time (The Guardian, Science)
- Karen Miga, who led the Telomere-to-Telemere Consortium, is named one of TIME’s 100 most influential people of 2022 (TIME, University of California)
- Spanish researchers obtain the first 100% genome sequence draft of the monkeypox virus. (EuroWeekly)
- More than a third of severely sick babies referred for rapid whole genome sequencing receive vital genetic diagnosis in latest study across the East of England. (Cambridge Network)
Image credit: canva
