Mobile Menu

Genomics Week in Brief: Week Ending 24th May

Struggling to keep up with the latest news in the genomics world? We’ve got you covered! In Week in Brief, we’ve collated the biggest stories from the past seven days, so you can catch up quickly.

Cancer research has been in the spotlight again this week…

The 100th version of the COSMIC knowledgebase has been released. Information has been added on over 300,000 new variants linked to human cancers (Sanger Institute).

A biomarker has been identified that can be used to predict a patient’s response to immunotherapy for kidney cancer. This opens new avenues for personalised therapeutics (Nature Medicine).

Leukaemia, in particular, has been highlighted…

A study has highlighted the importance of matching donor and recipient sex when using mouse xenotransplantation models to investigate conditions like leukaemia (HemaSphere).

Scientists have developed a potential new approach for leukaemia treatment, in which the diseased blood system is ‘deleted’ and simultaneously replaced with healthy cells from a donor (Nature).

There has been big updates in the neuroscience and psychiatry fields…

Researchers have used single-cell technologies to develop a map that details how genetic variants linked to schizophrenia affect different cell types in the brain (Science).

Ancient DNA hailing from past viral infections has been found to be expressed in the brain. Some have been linked to psychiatric disorders, including schizophrenia and bipolar disorder (Nature Communications).

A large-scale study of adolescents has revealed that mental disorders may be ‘transmitted’ through social networks formed within school environments. The study followed the individuals for over a decade, and suggested that the more classmates with a mental health condition, the more likely someone was to receive a diagnosis as an adult (JAMA Psychiatry).

Researchers have leveraged machine learning techniques to perform a large-scale analysis of gene regulation in the brain. They linked a number of regulatory elements to neurological and psychiatric disorders (Science).

And that’s not all…

A non-hormonal, sperm-specific approach has shown promise as a reversible male contraceptive, according to a new study in mice (Science).

A genetic test has been developed that could identify patients who will benefit most from weight-loss medication Wegovy, more commonly known as Ozempic (Journal of the Endocrine Society).

FInally, scientists have analysed platelets from infants who died of SIDS, identifying biomarkers that may help to predict risk in living children and aid in determining cause of death in victims (Scientific Reports).

Check out last week’s Week in Brief here.